Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614298 | 0.90 | PTPN11 (0.40) | GPR119FLT3PIK3R1PIK3CAPIM1 | |
| SCHEMBL28600236 | 0.86 | AAK1 (0.36) | GPR119FLT3PIK3R1PIK3CAPIM1 | |
| SCHEMBL30068780 | 0.86 | ELANE (0.47) | GPR119PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL25259725 | 0.86 | ELANE (0.47) | GPR119PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL28605059 | 0.81 | BRD4 (0.38) | GPR119PIK3R1PIK3CAPIM1MARK3 | |
| SCHEMBL28598143 | 0.81 | PIK3R1 (0.33) | FLT3PIK3R1PIK3CAPIM1MARK3 | |
| SCHEMBL22922572 | 0.81 | CYP1A2 (0.37) | GPR119FLT3USP30 | |
| SCHEMBL29556836 | 0.81 | GPR119 (0.37) | GPR119PIK3R1PIK3CAELANERET | |
| SCHEMBL28559315 | 0.81 | GPR119 (0.37) | GPR119PIK3R1PIK3CAELANERET | |
| SCHEMBL19411567 | 0.78 | AAK1 (0.38) | PIK3R1PIK3CAPIM1MARK3MAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214247-A | Azaindole derivative marrow cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-08-06 | — | — | CN | disclosed |