Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614298 | 0.87 | PTPN11 (0.40) | PIK3R1PIK3CAFLT3NFATC1DYRK1A | |
| SCHEMBL28600232 | 0.86 | GPR119 (0.38) | PIK3R1PIK3CAFLT3PIM1MARK3 | |
| SCHEMBL25259725 | 0.83 | ELANE (0.47) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL30068780 | 0.83 | ELANE (0.47) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL28598143 | 0.82 | PIK3R1 (0.33) | AAK1PIK3R1PIK3CAFLT3PIM1 | |
| SCHEMBL29556124 | 0.81 | MAP2K4 (0.39) | AAK1PIK3R1PIK3CATBK1MAP4K4 | |
| SCHEMBL28570718 | 0.81 | MAP2K4 (0.39) | AAK1PIK3R1PIK3CATBK1MAP4K4 | |
| SCHEMBL27821750 | 0.80 | AAK1 (0.35) | AAK1PIK3R1PIK3CAHTR6USP30 | |
| SCHEMBL28605059 | 0.79 | BRD4 (0.38) | PIK3R1PIK3CADYRK1APIM1MARK3 | |
| SCHEMBL22922572 | 0.78 | CYP1A2 (0.37) | FLT3USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214247-A | Azaindole derivative marrow cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-08-06 | — | — | CN | disclosed |