Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974616 | 0.81 | PBRM1 (0.41) | PBRM1TSHRTRPA1THRBSLC6A2 | |
| SCHEMBL2571472 | 0.80 | KMT2A (0.38) | PBRM1TSHRTHRBSLC6A2SLC6A4 | |
| SCHEMBL10400854 | 0.79 | AOC3 (0.57) | PBRM1TSHRSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL28393502 | 0.78 | SLC6A4 (0.50) | PBRM1TSHRSLC6A2SLC6A4CYP2D6 | |
| Iodomethane SCHEMBL18703954 | 0.78 | AOC3 (0.50) | PBRM1TSHRSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL734453 | 0.77 | PBRM1 (0.41) | PBRM1TSHRTRPA1SLC6A2SLC6A4 | |
| SCHEMBL7552631 | 0.77 | PABPC1 (0.50) | PBRM1TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL2208580 | 0.77 | PABPC1 (0.50) | PBRM1TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL28264000 | 0.77 | PBRM1 (0.42) | PBRM1TSHRTRPA1KMT2AMEN1 | |
| SCHEMBL6343043 | 0.76 | SLC6A4 (0.41) | TSHRTRPA1THRBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920062-A | Method for synthesizing venlafaxine by using fixed bed hydrogenation equipment | 合肥立方制药股份有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112920062-A | Method for synthesizing venlafaxine by using fixed bed hydrogenation equipment | 合肥立方制药股份有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-112920062-A | Method for synthesizing venlafaxine by using fixed bed hydrogenation equipment | 合肥立方制药股份有限公司 | 2021-06-08 | — | — | CN | disclosed |