Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973603 | 0.99 | MCL1 (0.50) | MCL1LIMK1MAPK1SMN1; SMN2HTT | |
| SCHEMBL17960334 | 0.84 | LMNA (0.58) | LIMK1MAPK1SMN1; SMN2HTTLMNA | |
| Lithium Ion SCHEMBL17960492 | 0.84 | LIMK1 (0.47) | MCL1LIMK1MAPK1SMN1; SMN2HTT | |
| SCHEMBL9433865 | 0.77 | LIMK1 (0.62) | LIMK1MAPK1SMN1; SMN2HTTLMNA | |
| SCHEMBL15697522 | 0.76 | MCL1 (0.54) | MCL1LIMK1MAPK1SMN1; SMN2PRNP | |
| SCHEMBL20937648 | 0.75 | MCL1 (0.58) | MCL1LIMK1MAPK1SMN1; SMN2PRNP | |
| SCHEMBL11558126 | 0.75 | MAPK1 (0.42) | LIMK1MAPK1SMN1; SMN2HTTMAPT | |
| SCHEMBL6652018 | 0.72 | KDM4E (0.59) | LIMK1MAPK1SMN1; SMN2LMNACD274 | |
| SCHEMBL8796666 | 0.71 | CYP1A2 (0.56) | MCL1LIMK1SMN1; SMN2HTTRXFP1 | |
| SCHEMBL4342220 | 0.71 | NPC1 (0.54) | MCL1LIMK1MAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873023-B | 3-alkyl-4-amido-bicyclo [4, 5, 0] hydroxamic acids as HDAC inhibitors | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |