Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973603 | 0.78 | MCL1 (0.50) | LIMK1SMN1; SMN2MAPK1HTTMAPT | |
| SCHEMBL13969608 | 0.77 | LIMK1 (1.00) | LIMK1SMN1; SMN2MAPK1IKBKBACLY | |
| SCHEMBL28600336 | 0.77 | MCL1 (0.49) | LIMK1SMN1; SMN2MAPK1HTTMAPT | |
| SCHEMBL17960334 | 0.76 | LMNA (0.58) | LIMK1SMN1; SMN2MAPK1HTTMAPT | |
| Lithium Ion SCHEMBL17960492 | 0.76 | LIMK1 (0.47) | LIMK1SMN1; SMN2MAPK1HTTIKBKB | |
| SCHEMBL9204067 | 0.75 | LIMK1 (0.54) | LIMK1IKBKBMAPTALDH1A1HSD17B10 | |
| SCHEMBL11559466 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPK1HTTMAPTALDH1A1 | |
| SCHEMBL16396113 | 0.72 | LIMK1 (0.68) | LIMK1MAPK1IKBKBACLYMAPT | |
| SCHEMBL6652018 | 0.72 | KDM4E (0.59) | LIMK1SMN1; SMN2MAPK1IKBKBMAPT | |
| SCHEMBL9434401 | 0.71 | TEAD1 (0.59) | HTTMAPTALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |