SCHEMBL28600646

SCHEMBL28600646

Cc1cc(-c2cnccn2)cc(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
CYP2D6 P10635 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
DHODH Q02127 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP1A2 P05177 1/20 0.35
PIM1 P11309 2/20 0.35
KIF11 P52732 2/20 0.34
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
NFKB1 P19838 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PRKCQ Q04759 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29262130 0.90 CYP2D6 (0.40) RXRARXRBCYP2D6CYP19A1CYP2C9
SCHEMBL8617736 0.84 CYP2D6 (0.43) CYP2D6CYP19A1CYP2C9CYP2C19DHODH
SCHEMBL4404396 0.77 KIF11 (0.57) RXRARXRBCYP2D6CYP19A1CYP2C9
SCHEMBL2406986 0.76 CYP2D6 (0.41) CYP2D6CYP19A1CYP2C9CYP2C19DHODH
SCHEMBL12632461 0.75 KIF11 (0.55) CYP2D6CYP19A1CYP2C9CYP2C19KIF11
SCHEMBL26415549 0.75 CYP2A6 (0.40) CYP2D6CYP19A1CYP2C9CYP2C19DHODH
SCHEMBL27878098 0.73 CYP2D6 (0.36) CYP2D6CYP19A1CYP2C9CYP2C19DHODH
SCHEMBL28522118 0.73 RXRB (0.60) RXRARXRBCYP2C9CYP2C19CYP1A2
SCHEMBL28799194 0.73 RXRA (0.42) RXRARXRBCYP19A1PIM1KIF11
SCHEMBL29809754 0.73 RXRA (0.42) RXRARXRBCYP19A1PIM1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105508-A Organometallic complex, top-emission light-emitting material, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2021-07-13 CN disclosed