Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537231 | 0.98 | ELANE (0.61) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL28392145 | 0.87 | ELANE (0.56) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| Phenol SCHEMBL28860331 | 0.86 | ELANE (0.50) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5536407 | 0.78 | ELANE (0.44) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL1821481 | 0.78 | FBP1 (0.45) | ELANEALDH1A1FBP1F2RL3AGPAT2 | |
| SCHEMBL24807093 | 0.78 | ELANE (0.44) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2761642 | 0.78 | ELANE (0.44) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5537227 | 0.78 | ELANE (0.41) | ELANEKDM4EALDH1A1FBP1F2RL3 | |
| SCHEMBL5544045 | 0.78 | ELANE (0.44) | ELANEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5546211 | 0.78 | ELANE (0.44) | ELANEKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | claimed |
| CN-117926287-A | Method for synthesizing 2-aminobenzoxazole derivative under electrochemical condition | 湘潭大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-113200969-B | PI3K alpha selective inhibitor and preparation method and application thereof | 中国药科大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-113200969-A | PI3K alpha selective inhibitor and preparation method and application thereof | 中国药科大学 | 2021-08-03 | — | — | CN | disclosed |