SCHEMBL5537231

SCHEMBL5537231

Cc1nc2c(C)cccc2o1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.61
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
FBP1 P09467 1/20 0.40
F2RL3 Q96RI0 3/20 0.40
PARP1 P09874 1/20 0.39
AGPAT2 O15120 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28600968 0.98 ELANE (0.59) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL28392145 0.89 ELANE (0.56) ELANEKDM4EMEN1ALDH1A1KMT2A
Phenol SCHEMBL28860331 0.88 ELANE (0.50) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL5077318 0.79 ELANE (0.44) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL5536407 0.79 ELANE (0.44) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL24807093 0.79 ELANE (0.44) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL2761642 0.79 ELANE (0.44) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL5537227 0.79 ELANE (0.41) ELANEKDM4EALDH1A1FBP1F2RL3
SCHEMBL5544045 0.79 ELANE (0.44) ELANEKDM4EMEN1ALDH1A1KMT2A
SCHEMBL1821481 0.79 FBP1 (0.45) ELANEALDH1A1FBP1F2RL3AGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794534-A Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof 尤尼根公司 2024-03-29 CN claimed
EP-4346810-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF Unigen, Inc. (US) 2024-04-10 EP disclosed
CN-117794534-A Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof 尤尼根公司 2024-03-29 CN disclosed
WO-2023097007-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-06-01 WO disclosed
CN-115557911-A 2-keto aryl benzoxazole compounds and synthesis method thereof 海南大学 2023-01-03 CN disclosed
WO-2022256624-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF UNIGEN, INC. (US) 2022-12-08 WO disclosed
EP-4019521-A1 AZAHETEROARYL COMPOUND AND APPLICATION THEREOF Blueray Therapeutics (Shanghai) Co., Ltd (CN) 2022-06-29 EP disclosed
CN-109370297-B Practical multifunctional efficient environment-friendly water-based paint remover as well as preparation method and application thereof 华阳新兴科技(天津)集团有限公司 2022-02-01 CN disclosed
WO-2021032004-A9 AZAHETEROARYL COMPOUND AND APPLICATION THEREOF 上海青煜医药科技有限公司 2021-03-25 WO disclosed
WO-2021032004-A1 AZAHETEROARYL COMPOUND AND APPLICATION THEREOF 上海青煜医药科技有限公司 2021-02-25 WO disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
US-20060025383-A1 Aminobenzoxazoles as therapeutic agents ABBOTT LABORATORIES 2006-02-02 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
EP-0893732-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2003-01-22 EP disclosed
US-5340694-A Containing hydrazine compound and cyanine dye; sensitivity, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1994-08-23 US disclosed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
EP-0315155-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-10 EP disclosed
EP-0306019-A2 Silver halide photographic material and method for forming an image FUJI PHOTO FILM CO., LTD. (JP) 1989-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025383-A1 Aminobenzoxazoles as therapeutic agents ABL1, MAP3K19, MAP3K20 ELANE 3598/4885KDM4E 403/4885MEN1 2995/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 ELANE 3771/4885KDM4E 4854/4885MEN1 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.