Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889799 | 0.80 | GAA (0.67) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL6649705 | 0.79 | ADRA1B (0.64) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL5167267 | 0.78 | ALOX5 (0.65) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL6650196 | 0.77 | GAA (0.61) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL28599553 | 0.76 | MAPT (0.56) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL6652519 | 0.75 | GAA (0.72) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL4717242 | 0.75 | IDO1 (0.65) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL20889821 | 0.74 | SALL4 (0.55) | GAASMN1; SMN2TP53HPGDMAPT | |
| SCHEMBL17833795 | 0.72 | BRD4 (0.78) | GAAMAPTBRD4 | |
| SCHEMBL28609935 | 0.71 | GAA (0.68) | GAASMN1; SMN2TP53HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096139-B | Preparation method of alpha-carbonyl amide derivative | 贵州大学 | 2021-03-02 | — | — | CN | disclosed |