Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593395 | 0.85 | ZDHHC7 (0.40) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL28593397 | 0.83 | KMT2A (0.40) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL28592709 | 0.74 | KMT2A (0.41) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL625321 | 0.73 | KMT2A (0.45) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL3095786 | 0.73 | KMT2A (0.40) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL3109691 | 0.73 | HSD17B10 (0.38) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL21787943 | 0.72 | BRD4 (0.45) | KMT2AHTTALDH1A1KDM4ECA12 | |
| SCHEMBL28595161 | 0.72 | HSD17B10 (0.42) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL1598651 | 0.72 | ALDH1A1 (0.46) | KMT2AHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL1674226 | 0.71 | KMT2A (0.41) | KMT2AHTTHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305143-B | Furan [2,3-c ] pyridine derivative and preparation method and application thereof | 济南新科医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |