Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598339 | 0.88 | MAOA (0.42) | HSD17B10KMT2AHTTRXFP1MAPK1 | |
| SCHEMBL28592709 | 0.87 | KMT2A (0.41) | HSD17B10KMT2AHTTMAPK1MAPT | |
| SCHEMBL1674226 | 0.83 | KMT2A (0.41) | HSD17B10KMT2AHTTMAPK1MAPT | |
| SCHEMBL3095786 | 0.82 | KMT2A (0.40) | HSD17B10KMT2AHTTRXFP1MAPT | |
| SCHEMBL3109691 | 0.81 | HSD17B10 (0.38) | HSD17B10KMT2AHTTMAPK1MAPT | |
| SCHEMBL16564102 | 0.81 | NPC1 (0.40) | HSD17B10KMT2AHTTSMN1; SMN2MAPT | |
| SCHEMBL3112985 | 0.79 | KMT2A (0.38) | HSD17B10KMT2AHTTMAPK1MAPT | |
| SCHEMBL625321 | 0.75 | KMT2A (0.45) | HSD17B10KMT2AHTTMAPTKDM4E | |
| SCHEMBL1598651 | 0.74 | ALDH1A1 (0.46) | HSD17B10KMT2AHTTMAPTKDM4E | |
| SCHEMBL28601048 | 0.72 | KMT2A (0.38) | HSD17B10KMT2AHTTMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305143-B | Furan [2,3-c ] pyridine derivative and preparation method and application thereof | 济南新科医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |