Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19396390 | 0.79 | RAB9A (0.34) | MEN1KMT2ARAB9AMAPTRIPK1 | |
| SCHEMBL15223025 | 0.77 | KDM4E (0.33) | MEN1KMT2A | |
| SCHEMBL29296514 | 0.72 | KMT2A (0.37) | MEN1KMT2AMAPTRIPK1ELANE | |
| SCHEMBL29296505 | 0.72 | KMT2A (0.37) | MEN1KMT2ARIPK1ELANEALDH1A1 | |
| SCHEMBL4438414 | 0.71 | MEN1 (0.34) | MEN1KMT2ARIPK1ELANEALDH1A1 | |
| SCHEMBL2563228 | 0.69 | KMT2A (0.35) | MEN1KMT2ARIPK1ELANEHPGD | |
| SCHEMBL29296516 | 0.68 | PGR (0.38) | MEN1KMT2ARAB9AMAPTRIPK1 | |
| SCHEMBL246455 | 0.63 | — | — | |
| SCHEMBL21407447 | 0.63 | NOTUM (0.42) | RAB9APTGS1PTGS2NPC1ALDH1A1 | |
| SCHEMBL445392 | 0.62 | HSP90AA1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121401-B | N-substituted carbonyl fluorosulfonamide compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2022-10-04 | — | — | CN | disclosed |
| CN-113121401-A | N-substituted carbonyl fluorosulfonamide compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2021-07-16 | — | — | CN | disclosed |