Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252464 | 0.79 | KCNQ3 (0.44) | TSHRMEN1NPC1MAPTRAB9A | |
| SCHEMBL2014424 | 0.78 | TSHR (0.52) | TSHRSRD5A2HSD17B10KDM4EMEN1 | |
| SCHEMBL31599679 | 0.78 | TSHR (0.52) | TSHRSRD5A2HSD17B10KDM4EMEN1 | |
| SCHEMBL27793384 | 0.78 | TSHR (0.57) | TSHRSRD5A2KMOKDM4EMEN1 | |
| SCHEMBL29514652 | 0.75 | TSHR (0.67) | TSHRSRD5A2KMOKDM4EMEN1 | |
| SCHEMBL110094 | 0.75 | TSHR (0.67) | TSHRSRD5A2KMOKDM4EMEN1 | |
| SCHEMBL16795752 | 0.75 | TSHR (0.48) | TSHRSRD5A2KMOHSD17B10KDM4E | |
| SCHEMBL13285771 | 0.74 | MAPT (0.40) | TSHRHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL2090891 | 0.73 | TSHR (0.64) | TSHRSRD5A2KMOKDM4EMEN1 | |
| SCHEMBL14672199 | 0.73 | TSHR (0.42) | TSHRSRD5A2KMOKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227175-A | Polymer composition comprising a thermoplastic elastomer with butadiene and styrene blocks and a compatible plasticizer | 米其林集团总公司 | 2021-08-06 | — | — | CN | claimed |