Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.65 |
| ▸ | HPGDS | O60760 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160653 | 0.83 | HIF1A (1.00) | HIF1AP2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14082174 | 0.82 | P2RX7 (0.73) | HIF1AP2RX7HPGDSSMN1; SMN2TRPV1 | |
| SCHEMBL20267109 | 0.81 | HPGDS (0.70) | HPGDSSMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL5598218 | 0.81 | HIF1A (0.85) | HIF1AP2RX7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16495906 | 0.80 | HPGDS (0.64) | HIF1AHPGDSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16496362 | 0.78 | NPC1 (0.58) | HPGDSSMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL16495680 | 0.78 | HPGDS (0.65) | HPGDSSMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL16496085 | 0.78 | HPGDS (0.65) | HPGDSSMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL16496356 | 0.77 | HPGDS (0.64) | HPGDSSMN1; SMN2NPC1RAB9ATRPV1 | |
| SCHEMBL28598668 | 0.77 | HIF1A (1.00) | HIF1AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |