SCHEMBL28601315

SCHEMBL28601315

CC(C)(C)c1ccc2c(c1)CN(c1ccc(C(=O)O)cc1)CO2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
SRD5A2 P31213 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RXRA P19793 5/20 0.40
RXRB P28702 4/20 0.40
RXRG P48443 2/20 0.40
RARG P13631 2/20 0.40
RARB P10826 1/20 0.40
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
USP2 O75604 1/20 0.38
EPHX2 P34913 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CHEK1 O14757 1/20 0.37
KIF11 P52732 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14694381 0.84 MAPT (0.41) MAPTALDH1A1GAASMN1; SMN2NPC1
SCHEMBL803057 0.84 MAPT (0.41) MAPTALDH1A1GAASMN1; SMN2NPC1
SCHEMBL39074 0.82 KCNH2 (0.41) MAPTLMNAALDH1A1GAASMN1; SMN2
SCHEMBL17703328 0.81 HRH3 (0.36) MAPTLMNAALDH1A1GAASMN1; SMN2
SCHEMBL15202639 0.81 ALDH1A1 (0.36) MAPTALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL17703329 0.80 ALDH1A1 (0.43) MAPTLMNAALDH1A1GAASMN1; SMN2
SCHEMBL803136 0.80 HRH3 (0.38) MAPTALDH1A1GAASMN1; SMN2KIF11
SCHEMBL25882937 0.78 PTGER4 (0.40) RXRARXRBRXRGMAPTEPHX2
SCHEMBL17703326 0.78 HSD11B1 (0.36) CA12CA1CA9MAPTLMNA
SCHEMBL17011368 0.78 MAPT (0.32) MAPTLMNAGAASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113167695-A Device for collecting volatile organic compounds 法国由内政部代表 2021-07-23 CN disclosed