SCHEMBL28601320

SCHEMBL28601320

NC(=O)CC(CC(CC(N)=O)C(N)=O)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293079 0.90 CA1 (0.39) CA1CA2KDM4EGMNNUSP2
SCHEMBL7029325 0.89 CA1 (0.32) CA1CA2LMNA
SCHEMBL1650677 0.87 SLC1A3 (0.43) CA1CA2ALDH1A1TDP1
SCHEMBL743997 0.87 SLC1A3 (0.43) CA1CA2ALDH1A1TDP1
SCHEMBL28893916 0.85 CA1 (0.34) CA1CA2ALDH1A1
SCHEMBL18301572 0.83
SCHEMBL11773067 0.82 SLC1A1 (0.36) CA1CA2KDM4EGMNNUSP2
SCHEMBL11154563 0.82 GABRR1 (0.35) CA1CA2KDM4EGMNNUSP2
SCHEMBL5867415 0.80 CPB2 (0.37) CA1CA2KDM4EGMNNUSP2
SCHEMBL3833965 0.80 CA2 (0.54) CA1CA2KDM4EGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227337-A Lubricant composition for ball joints 国际壳牌研究有限公司 2021-08-06 CN disclosed