SCHEMBL28601359

SCHEMBL28601359

CCCC(=O)Oc1cc(Cl)cc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.47
CTNNB1 P35222 1/20 0.47
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
CA2 P00918 2/20 0.39
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11878106 0.87 KMT2A (0.47) ALDH1A1KMT2AALOX15CA2RAB9A
SCHEMBL13228832 0.86 BCL9 (0.55) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL25246219 0.84 ESR1 (0.48) ALDH1A1KMT2AKDM4EGLAGAA
SCHEMBL27348590 0.82 FAAH (0.50) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL5468900 0.81 BCL9 (0.60) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL11229499 0.80 BCL9 (0.44) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL10748577 0.78 HPGD (0.53) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL28468806 0.78 BCL9 (0.49) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL11023644 0.77 BCL9 (0.70) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL13721468 0.77 BCL9 (0.47) BCL9CTNNB1ALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113164571-A Inhibition of ubiquitin-specific peptidase 9X 福马治疗股份有限公司 2021-07-23 CN disclosed