Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919286 | 0.89 | LMNA (0.35) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| SCHEMBL6914508 | 0.81 | — | — | |
| SCHEMBL18116052 | 0.81 | LMNA (0.41) | LMNACHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL23045236 | 0.80 | LMNA (0.46) | LMNACHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL8220411 | 0.79 | LPAR3 (0.47) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL17162566 | 0.78 | CHRM2 (0.39) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| SCHEMBL8220810 | 0.77 | LPAR3 (0.50) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| SCHEMBL16242411 | 0.77 | LPAR3 (0.50) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| SCHEMBL3332214 | 0.77 | LPAR3 (0.50) | ALDH1A1LMNAMAPTCACNA1BAPBA1 | |
| SCHEMBL1416536 | 0.77 | LPAR3 (0.50) | ALDH1A1LMNAMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227087-A | Macrocyclic compounds and their use in the treatment of disease | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |