Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116052 | 0.91 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14445313 | 0.91 | TSHR (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1246711 | 0.91 | CA12 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20094988 | 0.89 | ALOX15 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23045228 | 0.87 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28980314 | 0.87 | CHRM2 (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5250838 | 0.85 | — | — | |
| SCHEMBL5247574 | 0.85 | ACHE (0.47) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28995266 | 0.83 | CYP2C19 (0.47) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6960579 | 0.83 | CHRNB2 (0.47) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660202-B | Water-soluble prodrugs | 大日本住友制药肿瘤公司 | 2021-12-24 | — | — | CN | disclosed |
| WO-2021039616-A1 | COMBINATION THERAPY AND BIOMARKER INDICATING EFFICACY THEREOF | 大日本住友製薬株式会社 | 2021-03-04 | — | — | WO | disclosed |