Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL31329255 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA12CA1CA2 | |
| Octanoic Acid SCHEMBL29194737 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA12CA1CA2 | |
| Myristic Acid SCHEMBL28173391 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA12CA1CA2 | |
| Palmitic Acid SCHEMBL1858146 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA12CA1CA2 | |
| Dodecanoate SCHEMBL28954208 | 0.98 | ALDH1A1 (0.56) | ALDH1A1KDM4ECA12CA1CA2 | |
| Salicylic Acid SCHEMBL28538392 | 0.98 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Azelaic Acid SCHEMBL4039442 | 0.95 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA1CA2 | |
| Salicylic Acid SCHEMBL28366261 | 0.92 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 | |
| Dodecane SCHEMBL6692297 | 0.92 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 | |
| Sebacic Acid SCHEMBL29764185 | 0.92 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226470-A | Rifamycin analogs and antibody-drug conjugates thereof | 瑞泽恩制药公司 | 2021-08-06 | — | — | CN | disclosed |