Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391420 | 1.00 | PRMT1 (0.45) | PRMT1KMT2AGFERRAB9ANPC1 | |
| SCHEMBL29394293 | 0.79 | MEN1 (0.45) | PRMT1KMT2AGFERRAB9ANPC1 | |
| SCHEMBL28596239 | 0.79 | MEN1 (0.45) | PRMT1KMT2AGFERRAB9ANPC1 | |
| SCHEMBL2781010 | 0.72 | RAB9A (0.59) | KMT2ARAB9ANPC1MAPTPKM | |
| SCHEMBL29393690 | 0.71 | MEN1 (0.51) | KMT2ARAB9ANPC1MAPTMEN1 | |
| SCHEMBL21644023 | 0.71 | TDP1 (0.47) | PRMT1KMT2AGFERRAB9ANPC1 | |
| SCHEMBL28601530 | 0.71 | MEN1 (0.51) | KMT2ARAB9ANPC1MAPTMEN1 | |
| SCHEMBL2329401 | 0.69 | RAB9A (0.50) | PRMT1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL4349815 | 0.69 | NPC1 (0.65) | KMT2ARAB9ANPC1MAPTPKM | |
| SCHEMBL28388781 | 0.69 | CA1 (0.34) | KMT2ATDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164476-A | Small molecule inhibitor of DYRK1/CLK and application thereof | 代表亚利桑那大学的亚利桑那校董会 | 2021-07-23 | — | — | CN | disclosed |