Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545906 | 0.95 | HDAC1 (0.77) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL28257108 | 0.92 | POLB (0.74) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL9464308 | 0.91 | HTT (0.89) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL9464627 | 0.88 | POLB (0.88) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL15923232 | 0.88 | HDAC1 (0.67) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL30444767 | 0.88 | HDAC1 (0.79) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL11252751 | 0.87 | HTT (0.78) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL27922836 | 0.86 | HTT (0.72) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL28340846 | 0.86 | HTT (0.61) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL8401892 | 0.85 | TDP1 (0.73) | HTTHDAC6HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121433-A | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2021-07-16 | — | — | CN | claimed |
| CN-113121433-B | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2022-07-15 | — | — | CN | disclosed |
| CN-113121433-B | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2022-07-15 | — | — | CN | disclosed |
| CN-113121433-A | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121433-A | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2021-07-16 | — | — | CN | disclosed |