SCHEMBL9545906

SCHEMBL9545906

CCCCCCC(=O)Nc1cccc2cccnc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.77
HDAC4 P56524 5/20 0.77
HDAC6 Q9UBN7 4/20 0.77
HDAC3 O15379 3/20 0.77
HDAC7 Q8WUI4 3/20 0.77
HDAC2 Q92769 3/20 0.77
HDAC10 Q969S8 3/20 0.77
HDAC11 Q96DB2 3/20 0.77
HDAC8 Q9BY41 3/20 0.77
HDAC9 Q9UKV0 3/20 0.77
HDAC5 Q9UQL6 3/20 0.77
HTT P42858 1/20 0.72
POLB P06746 2/20 0.67
TDP1 Q9NUW8 2/20 0.63
LMNA P02545 2/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
CETP P11597 1/20 0.54
MEF2D Q14814 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28601651 0.95 HTT (0.76) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL15923232 0.93 HDAC1 (0.67) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL30444767 0.91 HDAC1 (0.79) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL28257108 0.89 POLB (0.74) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL9464308 0.89 HTT (0.89) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL1063949 0.88 HDAC1 (0.79) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL5327850 0.88 HDAC1 (0.79) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL5330269 0.88 HTT (0.92) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL14254963 0.88 HDAC1 (0.79) HDAC1HDAC4HDAC6HDAC3HDAC7
SCHEMBL5328065 0.87 HDAC1 (0.69) HDAC1HDAC4HDAC6HDAC3HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5127327-A None JP disclosed
JP-H05127327-A YELLOW DYESTUFF FORMING COUPLER AND SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL CONTAINING THE COUPLER FUJI PHOTO FILM CO LTD 1993-05-25 JP disclosed