Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.89 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.80 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.80 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.80 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.80 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.80 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.80 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.80 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.80 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464627 | 0.94 | POLB (0.88) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL11252751 | 0.93 | HTT (0.78) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL28601651 | 0.91 | HTT (0.76) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL14254963 | 0.90 | HDAC1 (0.79) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL5327850 | 0.90 | HDAC1 (0.79) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL30444767 | 0.90 | HDAC1 (0.79) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL5330269 | 0.90 | HTT (0.92) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL1063949 | 0.90 | HDAC1 (0.79) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL23080113 | 0.89 | POLB (0.76) | HTTHDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL9545906 | 0.89 | HDAC1 (0.77) | HTTHDAC6HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2290853-A | — | — | None | — | — | JP | disclosed |
| US-5182398-A | α-Amino acid diamide and use thereof as cupric ion-transporting ionophore | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1993-01-26 | — | — | US | disclosed |
| JP-H02290853-A | SELECTIVE TRANSPORTING IONOPHORE FOR BIVALENT COPPER ION | AGENCY OF IND SCIENCE & TECHNOL | 1990-11-30 | — | — | JP | disclosed |