Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586305 | 0.80 | CYP1A2 (0.52) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL8358132 | 0.78 | KCNA3 (0.59) | MTNR1ATDP1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3047898 | 0.77 | CYP1A2 (0.62) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL17435555 | 0.77 | CYP1A2 (0.48) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL16471027 | 0.77 | CYP1A2 (0.48) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL791971 | 0.77 | CYP1A2 (0.50) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL3779748 | 0.77 | CYP1A2 (0.48) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL30487942 | 0.77 | CYP1A2 (0.50) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL25888 | 0.76 | MTNR1A (0.45) | MTNR1ANQO2TDP1CYP1A2CYP2C19 | |
| SCHEMBL5515409 | 0.76 | MTNR1A (0.45) | MTNR1ANQO2TDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |