Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993409 | 1.00 | KDM4E (0.44) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL29429480 | 0.83 | KDM4E (0.48) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL22680304 | 0.83 | KDM4E (0.48) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL28601851 | 0.83 | KDM4E (0.48) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL24238766 | 0.82 | KDM4E (0.42) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL29993116 | 0.80 | SMN1; SMN2 (0.44) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL24238678 | 0.80 | SMN1; SMN2 (0.44) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL22045138 | 0.76 | KCNQ3 (0.41) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22679867 | 0.74 | KDM4E (0.53) | KDM4EJAK2JAK3LMNAMEN1 | |
| SCHEMBL28919382 | 0.74 | KDM4E (0.53) | KDM4EJAK2JAK3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166146-A | Other heteroaromatic compounds with anti-RSV activity | 爱尔兰詹森科学公司 | 2021-07-23 | — | — | CN | disclosed |