Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601758 | 0.76 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MAPTTP53POLB | |
| SCHEMBL29993409 | 0.76 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MAPTTP53POLB | |
| SCHEMBL24238703 | 0.75 | MAPT (0.33) | MAPTMEN1KMT2A | |
| SCHEMBL22045433 | 0.72 | PARP1 (0.40) | KCNQ3KCNQ2ALDH1A1RAB9AMAPT | |
| SCHEMBL22044749 | 0.71 | MEN1 (0.39) | KCNQ3KCNQ2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL22519009 | 0.68 | AR (0.39) | KCNQ3KCNQ2ALDH1A1RAB9AMAPT | |
| SCHEMBL1100173 | 0.67 | AR (0.55) | IP6K1ARPOLB | |
| SCHEMBL25199503 | 0.66 | ALDH1A1 (0.39) | ALDH1A1TSHRAOC3MEN1KMT2A | |
| SCHEMBL14098960 | 0.65 | KCNQ3 (0.48) | KCNQ3KCNQ2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24196359 | 0.65 | AR (0.42) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020109224-A1 | FURTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-06-04 | — | — | WO | disclosed |