Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA7 | P43166 | 6/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129039 | 0.79 | CA12 (0.56) | CA12CA7CA14CA9HTT | |
| SCHEMBL6534021 | 0.79 | CA12 (0.68) | CA12CA7CA14CA9CA2 | |
| SCHEMBL18423665 | 0.78 | LMNA (0.47) | CA12CA7CA14CA9CA2 | |
| SCHEMBL24990193 | 0.76 | CA2 (0.59) | CA12CA7CA14CA9CA2 | |
| SCHEMBL18109149 | 0.76 | CA12 (0.65) | CA12CA7CA14CA9CA2 | |
| SCHEMBL2112943 | 0.74 | CA2 (0.65) | CA12CA7CA14CA9CA2 | |
| SCHEMBL28101227 | 0.73 | MAPT (0.59) | HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL27870560 | 0.73 | CA2 (0.55) | CA12CA7CA14CA9CA2 | |
| SCHEMBL21686856 | 0.73 | CA2 (0.55) | CA12CA7CA14CA9CA2 | |
| SCHEMBL195152 | 0.73 | CA2 (0.55) | CA12CA7CA14CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166081-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |