Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318013 | 0.83 | TDP1 (0.37) | LMNAHSD17B10TDP1MAOAMAOB | |
| SCHEMBL21187934 | 0.81 | TDP1 (0.38) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL25736759 | 0.79 | TSHR (0.38) | HSD17B10TSHRTDP1MAOAMAOB | |
| SCHEMBL7923566 | 0.79 | CA2 (0.42) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL9281818 | 0.77 | MAOA (0.44) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL1437011 | 0.76 | TDP1 (0.40) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL25736714 | 0.76 | CA2 (0.33) | TSHRTDP1CA12CA14CA1 | |
| SCHEMBL21261831 | 0.76 | TDP1 (0.42) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL19400336 | 0.76 | MAOA (0.39) | TDP1MAOAMAOBCA12CA14 | |
| SCHEMBL89258 | 0.76 | CA1 (0.38) | TSHRTDP1MAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114072412-B | Tricyclic compound, pharmaceutical composition and application thereof | 深圳铂立健医药有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-114072412-A | Tricyclic compound, pharmaceutical composition and application thereof | 深圳铂立健医药有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-113214294-A | Tricyclic compound, pharmaceutical composition and application thereof | 深圳铂立健医药有限公司 | 2021-08-06 | — | — | CN | disclosed |