Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852555 | 0.92 | MAPK14 (0.54) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2848681 | 0.91 | MAPT (0.47) | CCR1MAPK14MAPTGAALMNA | |
| SCHEMBL2852672 | 0.85 | MAPT (0.60) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2853390 | 0.84 | CCR1 (0.49) | CCR1MAPTGAALMNAPKM | |
| SCHEMBL2855798 | 0.83 | MAPT (0.45) | CCR1MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL2856261 | 0.82 | MAPT (0.56) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2853491 | 0.82 | ALDH1A1 (0.55) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2852439 | 0.81 | MAPT (0.56) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2860462 | 0.80 | MAPT (0.55) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2857236 | 0.79 | MAPT (0.54) | MAPK14MAPTGAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |