Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856278 | 0.92 | MAPT (0.56) | MAPTHSP90AA1NPSR1KDM4EMEN1 | |
| SCHEMBL2857246 | 0.89 | MAPT (0.57) | CCR1MAPTNPSR1LMNAPKM | |
| SCHEMBL2852375 | 0.86 | CCR1 (0.63) | CCR1MAPTHSP90AA1NPSR1MEN1 | |
| SCHEMBL2860847 | 0.85 | CCR1 (0.55) | CCR1MAPTHSP90AA1NPSR1KDM4E | |
| SCHEMBL2854221 | 0.85 | MAPT (0.51) | CCR1MAPTHSP90AA1NPSR1KDM4E | |
| SCHEMBL2852672 | 0.85 | MAPT (0.60) | MAPTKMT2AGAALMNAPKM | |
| SCHEMBL2856261 | 0.84 | MAPT (0.56) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL2860246 | 0.84 | CCR1 (0.47) | CCR1MAPTMEN1KMT2AGAA | |
| SCHEMBL2848681 | 0.82 | MAPT (0.47) | CCR1MAPTKDM4EGAALMNA | |
| SCHEMBL2853491 | 0.82 | ALDH1A1 (0.55) | MAPTGAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |