Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856556 | 0.94 | CCR1 (0.54) | CCR1MAPK14L3MBTL1 | |
| SCHEMBL2853351 | 0.92 | CCR1 (0.62) | CCR1KDM4E | |
| SCHEMBL2857073 | 0.92 | CCR1 (0.48) | CCR1MAPK14KDM4EALDH1A1POLB | |
| SCHEMBL2862837 | 0.91 | CCR1 (0.61) | CCR1L3MBTL1KDM4E | |
| SCHEMBL2850732 | 0.91 | CCR1 (0.53) | CCR1 | |
| SCHEMBL2849956 | 0.91 | CCR1 (0.62) | CCR1MAPT | |
| SCHEMBL2861243 | 0.91 | KDM4E (0.52) | CCR1MAPK14KDM4EALDH1A1POLB | |
| SCHEMBL2863198 | 0.90 | CCR1 (0.50) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2856304 | 0.90 | KEAP1 (0.53) | CCR1MAPK14KDM4EALDH1A1POLB | |
| SCHEMBL2854330 | 0.90 | CCR1 (0.52) | CCR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |