Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.61 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853351 | 0.91 | CCR1 (0.62) | CCR1KDM4ENPSR1 | |
| SCHEMBL2860247 | 0.91 | CCR1 (0.59) | CCR1L3MBTL1KDM4E | |
| SCHEMBL2850732 | 0.91 | CCR1 (0.53) | CCR1 | |
| SCHEMBL2854324 | 0.90 | CCR1 (0.51) | CCR1 | |
| SCHEMBL2856556 | 0.89 | CCR1 (0.54) | CCR1L3MBTL1MLYCD | |
| SCHEMBL2849956 | 0.87 | CCR1 (0.62) | CCR1NPSR1 | |
| SCHEMBL2854330 | 0.85 | CCR1 (0.52) | CCR1 | |
| SCHEMBL2852941 | 0.84 | POLB (0.44) | CCR1KDM4E | |
| SCHEMBL2853349 | 0.84 | CCR1 (0.46) | CCR1KDM4E | |
| SCHEMBL2856460 | 0.84 | CCR1 (0.65) | CCR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |