Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454084 | 0.81 | KMT2A (0.47) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| SCHEMBL4910933 | 0.75 | FSCN1 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL1558411 | 0.75 | MEN1 (0.47) | KMT2AMEN1TSHRNPSR1ALDH1A1 | |
| SCHEMBL27492999 | 0.73 | CSNK2A1 (0.35) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL741752 | 0.73 | NPSR1 (0.64) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| SCHEMBL5603988 | 0.73 | TSPO (0.56) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| SCHEMBL7985338 | 0.73 | KMT2A (0.54) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| Hydrochloric Acid SCHEMBL8550497 | 0.71 | NPSR1 (0.61) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| SCHEMBL8044893 | 0.71 | NPSR1 (0.61) | KMT2AMEN1TSHRTRPM8NPSR1 | |
| SCHEMBL27583970 | 0.71 | NPC1 (0.54) | KMT2AMEN1TSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248396-B | Preparation method of chlorobenzene para-aminated compound mediated by high-valence iodine reagent | 湖北工业大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113336665-B | Preparation method of bromobenzene para-aminated compound mediated by high-valence iodine reagent | 湖北工业大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113336665-A | Preparation method of bromobenzene para-aminated compound mediated by high-valence iodine reagent | 湖北工业大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113248396-A | Preparation method of chlorobenzene para-aminated compound mediated by high-valence iodine reagent | 湖北工业大学 | 2021-08-13 | — | — | CN | disclosed |