Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 7/20 | 0.42 |
| ▸ | ECE1 | P42892 | 6/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | KLK8 | O60259 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK2 | P20151 | 1/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23881868 | 0.88 | MME (0.52) | CASP1ACP3MMEECE1ACE2 | |
| SCHEMBL23881694 | 0.87 | CASP1 (0.51) | CASP1ACP3MMEECE1ACE2 | |
| SCHEMBL28598146 | 0.86 | ACE2 (0.46) | CASP1MMEECE1ACE2 | |
| SCHEMBL28607515 | 0.85 | ACE2 (0.45) | MMEECE1ACE2 | |
| SCHEMBL28606134 | 0.84 | F2 (0.43) | MMEECE1ACE2KLK8F2 | |
| SCHEMBL28598306 | 0.82 | MEN1 (0.45) | MMEECE1ACE2 | |
| SCHEMBL28607514 | 0.81 | ACE2 (0.46) | MMEECE1ACE2F2PLAU | |
| SCHEMBL28610449 | 0.80 | F2 (0.47) | MMEECE1ACE2KLK8F2 | |
| SCHEMBL28607881 | 0.80 | NPC1 (0.45) | MMEECE1ACE2KLK8F2 | |
| SCHEMBL28597382 | 0.80 | ATM (0.51) | MMEECE1ACE2F2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |