SCHEMBL2860366

SCHEMBL2860366

O=Cc1c(-c2ccccc2)n(Cc2ccccc2)c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.59
ALDH1A1 P00352 6/20 0.59
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
KDM4E B2RXH2 3/20 0.54
POLB P06746 2/20 0.54
USP2 O75604 1/20 0.54
CYP19A1 P11511 1/20 0.54
P2RX4 Q99571 1/20 0.53
PSMD14 O00487 1/20 0.52
NPSR1 Q6W5P4 2/20 0.51
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NTRK1 P04629 1/20 0.48
THRB P10828 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
MAPK1 P28482 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2851555 0.83 ALDH1A1 (0.65) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL28216521 0.81 CYP19A1 (0.58) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL2345535 0.81 KMT2A (0.60) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL10938208 0.81 ALDH1A1 (0.61) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL10624841 0.80 LMNA (0.79) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL2853959 0.78 ALDH1A1 (0.62) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL9584036 0.78 CYP19A1 (0.58) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL29952318 0.78 KMT2A (0.85) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL9187427 0.77 ALDH1A1 (0.57) LMNAALDH1A1MEN1KMT2AKDM4E
SCHEMBL27852704 0.77 ALDH1A1 (0.78) LMNAALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248779-B1 INTERMEDIATE FILM FOR LAMINATED GLASS AND LAMINATED GLASS SEKISUI CHEMICAL CO LTD (JP) 2016-08-31 EP disclosed
US-8361625-B2 Interlayer film for laminated glass and laminated glass SEKISUI CHEMICAL CO., LTD. (JP) 2013-01-29 US disclosed
CN-101910084-B Interlayer film for laminated glass and laminated glass SEKISUI CHEMICAL CO LTD 2012-07-18 CN disclosed
CN-101910084-A Interlayer film for laminated glass and laminated glass SEKISUI CHEMICAL CO LTD 2010-12-08 CN disclosed
EP-2248779-A1 INTERMEDIATE FILM FOR LAMINATED GLASS AND LAMINATED GLASS Orient Chemical Industries Co., Ltd. (JP) 2010-11-10 EP disclosed
US-20100279150-A1 INTERLAYER FILM FOR LAMINATED GLASS AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2010-11-04 US disclosed
US-5840902-A REACTING PICOLINE WITH ALKYLENE OXIDE IN PRESENCE OF ACID IN WATER OR MIXTURE OF WATER AND POLAR SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
EP-0477844-B1 Indole compounds and their use ORIENT CHEMICAL IND (JP) 1997-01-02 EP disclosed
US-5401438-A Photostabilizers ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-28 US disclosed
US-5296519-A Coatings ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1994-03-22 US disclosed
EP-0477844-A1 Indole compounds and their use ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1992-04-01 EP disclosed