SCHEMBL28603871

SCHEMBL28603871

COCOc1cc(OC)c(C)c(OCOC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 1/20 0.38
ROR1 Q01973 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
FYN P06241 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15114736 0.96 TNFRSF1A (0.40) TNFRSF1AROR1MEN1KMT2ARXFP1
SCHEMBL28612479 0.92 CYP3A4 (0.39) ROR1MEN1KMT2ARXFP1CA12
SCHEMBL1606682 0.88 ALDH1A1 (0.42) ROR1MEN1KMT2ACA12CA1
SCHEMBL28618565 0.82 CYP3A4 (0.47) MEN1KMT2ARXFP1MAPTBACE1
SCHEMBL28598759 0.82 NPSR1 (0.35) TNFRSF1AROR1HDAC3HDAC4HDAC1
SCHEMBL28614800 0.81 CYP3A4 (0.45) TNFRSF1AROR1MEN1KMT2AHDAC3
SCHEMBL15114734 0.79 FYN (0.49) FYNCA9TUBB4ATUBBTUBA3C
SCHEMBL6934496 0.78 CYP3A4 (0.38) ROR1CA12CA1CA2CA7
SCHEMBL15434469 0.77 NQO1 (0.44) MEN1KMT2ARXFP1CA12CA1
SCHEMBL3394032 0.76 CA2 (0.54) ROR1MEN1KMT2AHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293493-B Novel benzhydryl compounds with mycobacterium tuberculosis inhibiting activity 清华大学 2021-08-03 CN disclosed