Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611414 | 0.84 | KDR (0.39) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL28612682 | 0.82 | PBRM1 (0.41) | PBRM1 | |
| SCHEMBL28603913 | 0.81 | EPHX2 (0.38) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL1501833 | 0.79 | TNKS2 (0.54) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL19085276 | 0.79 | TSHR (0.51) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL28244738 | 0.78 | BRD4 (0.44) | ALDH1A1TNKS2LMNAMAOB | |
| SCHEMBL28606293 | 0.75 | MAOB (0.48) | ALDH1A1LMNAMAOB | |
| SCHEMBL28599110 | 0.74 | HTT (0.53) | ALDH1A1CYP1A2HPGDHSD17B10KDM4E | |
| Aza-Flavanone SCHEMBL1501991 | 0.73 | MAPT (0.56) | KMT2AALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL29353603 | 0.68 | KMT2A (0.56) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |