Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608462 | 0.84 | ALDH1A1 (0.38) | PBRM1TP53 | |
| SCHEMBL28608529 | 0.83 | RAB9A (0.38) | TP53 | |
| SCHEMBL28608514 | 0.82 | MAPT (0.39) | TP53 | |
| SCHEMBL28610945 | 0.82 | TGM2 (0.41) | TGM2CES1 | |
| SCHEMBL28604175 | 0.82 | KMT2A (0.48) | PBRM1 | |
| SCHEMBL28600852 | 0.82 | HTT (0.43) | TGM2CES1TP53 | |
| SCHEMBL28603953 | 0.80 | KDM4E (0.48) | — | |
| SCHEMBL28612447 | 0.76 | MEN1 (0.43) | TGM2CES1TP53 | |
| SCHEMBL28601603 | 0.75 | MAPT (0.50) | — | |
| SCHEMBL28606293 | 0.72 | MAOB (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |