Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603953 | 0.87 | KDM4E (0.48) | MAOBBRD4MAPT | |
| SCHEMBL1501833 | 0.83 | TNKS2 (0.54) | MAOBBRD4ALDH1A1LMNAMAPT | |
| SCHEMBL28603932 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL28601603 | 0.81 | MAPT (0.50) | BRD4LRRK2CYP19A1ALDH1A1LMNA | |
| SCHEMBL2349856 | 0.81 | TRPM5 (0.43) | BRD4MAPT | |
| SCHEMBL28610945 | 0.81 | TGM2 (0.41) | MAOBBRD4MAPT | |
| Aza-Flavanone SCHEMBL1501991 | 0.80 | MAPT (0.56) | MAOBBRD4CYP19A1ALDH1A1LMNA | |
| SCHEMBL28612430 | 0.79 | MAOA (0.40) | MAOB | |
| SCHEMBL14522626 | 0.79 | TRPM5 (0.44) | BRD4MAPT | |
| SCHEMBL28244738 | 0.78 | BRD4 (0.44) | MAOBBRD4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |