Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144501 | 0.88 | APAF1 (0.54) | MAOANSD2APAF1TDP2ALDH1A1 | |
| SCHEMBL23271778 | 0.84 | IDO1 (0.58) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL30004106 | 0.84 | IDO1 (0.58) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL125609 | 0.81 | NSD2 (0.55) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL122441 | 0.79 | NSD2 (0.62) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL11362829 | 0.78 | MAOA (0.76) | MAOAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30003398 | 0.78 | NSD2 (0.43) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL23271809 | 0.78 | NSD2 (0.43) | MAOANSD2ALDH1A1LMNAMAPT | |
| SCHEMBL2126261 | 0.77 | APAF1 (0.68) | MAOANSD2APAF1TDP2ALDH1A1 | |
| SCHEMBL14207782 | 0.77 | MAOA (0.61) | MAOANSD2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135863-B | EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions | 特拉维夫医疗中心医学研究基础设施和保健服务基金会 | 2021-07-27 | — | — | CN | disclosed |