Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917265 | 0.82 | PLG (0.40) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL14972795 | 0.75 | — | — | |
| SCHEMBL2340454 | 0.74 | PLG (0.42) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL22571032 | 0.74 | PLG (0.42) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL2340457 | 0.74 | PLG (0.42) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL2340458 | 0.74 | PLG (0.42) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL27889792 | 0.73 | KMT2A (0.46) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL19227668 | 0.73 | LMNA (0.41) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL13537167 | 0.71 | PLG (0.40) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL7683514 | 0.71 | TDP1 (0.46) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |