Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656754 | 0.81 | SIGMAR1 (0.51) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL28406248 | 0.80 | PARP1 (0.59) | GLRA1HSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL9781914 | 0.79 | PKM (0.54) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28919582 | 0.79 | NR1H2 (0.45) | GLRA1HSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL12324603 | 0.78 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2NPSR1NPC1 | |
| SCHEMBL14646669 | 0.78 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2NPSR1NPC1 | |
| SCHEMBL2680992 | 0.78 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2NPSR1NPC1 | |
| Hydrochloric Acid SCHEMBL29121517 | 0.77 | SMN1; SMN2 (0.51) | MEN1KMT2ATSHRSMN1; SMN2NPSR1 | |
| SCHEMBL28599521 | 0.77 | SMN1; SMN2 (0.41) | GLRA1HSD17B10HPGDLMNASMN1; SMN2 | |
| SCHEMBL28236192 | 0.76 | GLRA1 (0.51) | GLRA1HSD17B10ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105395-B | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113105395-A | 4-phenylsulfonyl-1-trihydroxy benzoyl piperazine-2-carboxamide derivative and preparation method and application thereof | 山东大学 | 2021-07-13 | — | — | CN | disclosed |