Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850857 | 1.00 | TP53 (0.46) | TP53P2RX7CNR1NPSR1TAAR1 | |
| SCHEMBL2860669 | 0.96 | TAAR1 (0.46) | TP53P2RX7CNR1TAAR1MAPT | |
| SCHEMBL2863154 | 0.95 | MAPT (0.45) | TP53P2RX7MAPTLMNATSHR | |
| SCHEMBL2850618 | 0.92 | MAPT (0.44) | TP53P2RX7CNR1TAAR1MAPT | |
| SCHEMBL2857768 | 0.91 | CNR1 (0.43) | TP53P2RX7CNR1NPSR1TAAR1 | |
| SCHEMBL2859861 | 0.91 | TAAR1 (0.51) | TP53CNR1NPSR1TAAR1MAPT | |
| SCHEMBL2855547 | 0.91 | TAAR1 (0.54) | P2RX7CNR1NPSR1TAAR1MAPT | |
| SCHEMBL2861752 | 0.91 | MAPT (0.43) | TP53P2RX7MAPTLMNATSHR | |
| SCHEMBL2860468 | 0.90 | KDM4E (0.44) | P2RX7CNR1TAAR1MAPTLMNA | |
| SCHEMBL2854309 | 0.90 | MAPT (0.42) | TP53P2RX7MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |