Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861752 | 0.96 | MAPT (0.43) | MAPTP2RX7TSHRL3MBTL1SMO | |
| SCHEMBL2854309 | 0.95 | MAPT (0.42) | MAPTP2RX7TSHRL3MBTL1SMO | |
| SCHEMBL2860458 | 0.95 | TP53 (0.46) | MAPTP2RX7TSHRL3MBTL1TP53 | |
| SCHEMBL2850857 | 0.95 | TP53 (0.46) | MAPTP2RX7TSHRL3MBTL1TP53 | |
| SCHEMBL2854346 | 0.95 | MAPT (0.52) | MAPTP2RX7TSHRL3MBTL1TP53 | |
| SCHEMBL2856562 | 0.95 | MAPT (0.48) | MAPTP2RX7TSHRL3MBTL1SMO | |
| SCHEMBL2854598 | 0.93 | TRPV1 (0.41) | MAPTP2RX7TSHRL3MBTL1SMO | |
| SCHEMBL2860669 | 0.90 | TAAR1 (0.46) | MAPTP2RX7TP53CCR1KDM4E | |
| SCHEMBL2855493 | 0.90 | P2RX7 (0.48) | MAPTP2RX7SMOCCR1MAPK1 | |
| SCHEMBL2855711 | 0.90 | P2RX7 (0.42) | MAPTP2RX7SMOTP53CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |