Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7184944 | 0.92 | KDM4E (0.35) | KDM4EPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL723919 | 0.80 | — | — | |
| SCHEMBL19604899 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10494674 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL10494657 | 0.78 | ACHE (0.32) | ALDH1A1TSHR | |
| Acetic Acid SCHEMBL19991790 | 0.78 | PAOX (0.47) | KDM4EALDH1A1PAOXTSHRMAPT | |
| Acetic Acid SCHEMBL27888297 | 0.77 | ALDH1A1 (0.38) | KDM4EPOLBALDH1A1PAOXTSHR | |
| Acetic Acid SCHEMBL7917433 | 0.77 | ALDH1A1 (0.38) | KDM4EPOLBALDH1A1PAOXTSHR | |
| Acetic Acid SCHEMBL3421514 | 0.77 | ANPEP (0.47) | KDM4EALDH1A1PAOXGSR | |
| Acetic Acid SCHEMBL27984383 | 0.75 | ALDH1A1 (0.40) | KDM4EPOLBALDH1A1PAOXTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207416-B1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | IMERYS FILTRATION MINERALS INC (US) | 2018-11-07 | — | — | EP | disclosed |
| US-20100239679-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | WORLD MINERALS, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| EP-2207416-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | World Minerals, Inc. (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009045941-A1 | ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM | WORLD MINERALS, INC. (US) | 2009-04-09 | — | — | WO | disclosed |