Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 9/20 | 0.43 |
| ▸ | MME | P08473 | 8/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.42 |
| ▸ | KLK8 | O60259 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLK2 | P20151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23881683 | 0.89 | MMP8 (0.52) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881850 | 0.87 | ACE2 (0.50) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881665 | 0.81 | ECE1 (0.50) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881812 | 0.81 | ACE2 (0.52) | ACE2ECE1MMEKYNU | |
| SCHEMBL23881888 | 0.80 | ECE1 (0.57) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881893 | 0.79 | ACE2 (0.48) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881969 | 0.79 | ACE2 (0.55) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL23881738 | 0.78 | CASP1 (0.51) | MMP8MMP14ACE2ECE1MME | |
| SCHEMBL28606124 | 0.78 | CASP1 (0.41) | MMP8MMP14CASP1 | |
| SCHEMBL23881880 | 0.78 | ATM (0.52) | MMP8MMP14ACE2ECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |