Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440861 | 1.00 | BTK (0.48) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL23440866 | 1.00 | BTK (0.48) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL28973264 | 0.88 | BTK (0.46) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2975559 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2975553 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2975557 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2975551 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2976522 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL2975555 | 0.86 | BTK (0.47) | BTKDRD2DRD3KDM1AMAOB | |
| SCHEMBL29191917 | 0.85 | DRD2 (0.42) | BTKDRD2DRD3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |