Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440861 | 0.88 | BTK (0.48) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL28606233 | 0.88 | BTK (0.48) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL23440866 | 0.88 | BTK (0.48) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL28984106 | 0.86 | EPHX1 (0.46) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL28984107 | 0.86 | EPHX1 (0.46) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL30472899 | 0.85 | DRD2 (0.43) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL30199537 | 0.84 | DRD2 (0.41) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL11921121 | 0.82 | EPHX1 (0.51) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL224930 | 0.82 | EPHX1 (0.51) | BTKDRD2EPHX1KDM1AMAOB | |
| SCHEMBL224929 | 0.82 | EPHX1 (0.51) | BTKDRD2EPHX1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117545752-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115835866-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-03-21 | — | — | CN | disclosed |