Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860669 | 0.91 | TAAR1 (0.46) | MAPTKDM4EALDH1A1LMNACCR1 | |
| SCHEMBL2852955 | 0.91 | KDM4E (0.44) | SLC7A5MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL2853462 | 0.90 | TRPV1 (0.42) | MAPTCCR1TAAR1ABCB1P2RX7 | |
| SCHEMBL2850618 | 0.90 | MAPT (0.44) | MAPTLMNACCR1TAAR1ABCB1 | |
| SCHEMBL2857238 | 0.88 | CCR1 (0.43) | MAPTLMNACCR1TAAR1ABCB1 | |
| SCHEMBL2857600 | 0.88 | CNR1 (0.46) | MAPTCCR1TAAR1ABCB1P2RX7 | |
| SCHEMBL2852505 | 0.88 | ABCB1 (0.48) | MAPTALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL2860458 | 0.88 | TP53 (0.46) | MAPTLMNATAAR1P2RX7NPSR1 | |
| SCHEMBL2850857 | 0.88 | TP53 (0.46) | MAPTLMNATAAR1P2RX7NPSR1 | |
| SCHEMBL2854891 | 0.87 | ABCB1 (0.52) | ALDH1A1LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |